ChemSim - your resource for process simulation
- Determine the best, most economic, plant design
- Examine plant retrofit options and other process improvements
- Determine process fit requirements for new products
- Examine process economics for new processes or products
- Compare process alternatives
- Develop robust schedules and eliminate bottlenecks for batch processes
Process Simulation and Scheduling
Biofuels - Biodiesel and Bioethanol
ChemSim's chemical and biochemical
engineers are experts in applying process simulation tools to the design
and optimization of industrial chemical processes. ChemSim works directly
with client engineers to solve important business and engineering problems.
Our goal is to maximize the return on your modeling investment.
Most recent presentation:
"How Process Simulation is used in Biogen Idec to Optimize Manufacturing Processes" - IBC Conference, Rhode Island,
Alex Fotopoulos - Biogen Idec, Chris Antoniou
- Biogen Idec, Ian Gosling - ChemSim
- Consulting, on all aspects of process simulation
- Advice on the best process simulator for your needs
- Expertise in many flowsheet simulators including Aspen One™, Pro/II™, BatchPlus™, SuperPro™
and SchedulePro™, PD-PLUS™, and ChemCAD.
- Software Integration solutions
We have many years of
experience applying the suite of tools developed by Aspen
Technology so if you have problems regressing physical properties,
converging a large flowsheet, or implementing a 'user' model we can help.
Today, more groups are looking
at dynamic modeling using Aspen Dynamics and Aspen Custom Modeler (ACM).
However with these products it is important to structure the problem
in a manner which facilitates solution of the equations. We have the
experience to smooth the migration from the steady state, Aspen Plus
solution, to the most appropriate dynamic solution.
For dynamic modeling, an alternative
approach to ACM and Aspen Dynamics is the
modeling environment of gPROMS™,
from PSE Ltd. This newer
product shares it's pedigree with Aspen Dynamics, as both originate from
SpeedUp - the original tool for dynamic flow sheet simulation. However
gPROMS incorporates the latest in algorithms for solving tough numerical
For bioprocess simulation our team has had good experience
with the Intelligen suite of products, SuperPro Designer and SchedulePro. We
can also provide custom solutions with this suite, utilizing Excel® with a Visual
If you need little more than
a spreadsheet for calculations, or you need an equivalent to Visio®
to quickly layout a process flow diagram, or have a batch process why
not try SuperPro Designer from Intelligen!
For process scheduling problems where Project® is not suitable,
There are many simulation
tools available, ranging in complexity and price! We use the most suitable
tool to solve the clients problem.
Biopharmaceutical Process Simulation and Scheduling
The optimal operation of Biopharmaceutical
processes poses a unique set of problems for the process engineer. Although
the process is operating in a validated environment there is still the
need to improve productivity and reduce costs.
For batch operations in multiproduct
facilities use the combination of SuperPro™
to investigate scheduling, resource requirements, bottlenecks, etc. See
a simplified example of modeling a multiproduct biopharmaceutical facility.
For a more in depth discussion
of Bioprocess Simulation Strategies in pdf format. "Optimizing
productivity in multiproduct batch facilities"
(Genetic Engineering News - Sept 2003.)
And for an updated summary
on the latest tools and techniques used for bioprocess simulation see
our article; "Simulation tools in the optimization of biopharmaceutical processing".
(Innovations in Pharmaceutical Technology - Winter 2010)
For more information, see
a brochure of our capabilities.